The Magazine for Sleep Professionals
Saturday, April 4, 2026
Alkermes plc, announced the initiation of the Brilliance Studies, a phase 3 program evaluating the safety and efficacy of alixorexton compared to placebo in adults with narcolepsy type 1 (NT1) and narcolepsy type 2 (NT2). Alixorexton is the company’s novel, investigational, oral, selective orexin 2 receptor (OX2R) agonist in development […]
Eisai Inc. announced today that screening for global Study E2086-G000-202 (Study 202) to assess the efficacy, safety and tolerability of E2086, a novel selective orexin-2 receptor, is now registered on ClinicalTrials.gov as NCT07493265. Study sites are also planned for Canada, China, Europe, Japan, and South Korea. Study 202 is a three-period, […]
Narcolepsy is a chronic condition in which someone feels excessively sleepy, occasionally falling asleep without warning. This can have a major impact on their daily lives, affecting not only their education and employment, but also their ability to drive, their relationships, and their emotional health. “It’s quite striking when you’re […]
University of Texas at Dallas researchers, in partnership with Texas-based biotech company EnLiSense, have demonstrated a pioneering wearable perspiration-based sensor that measures two key hormones that regulate the body’s sleep-wake cycle. The electrochemical sensor continuously monitors cortisol, which promotes wakefulness, and melatonin, which signals the body to sleep. The bioengineers […]
Nexalin Technology, Inc. announced continued advancement toward its planned pivotal clinical trial evaluating HALO™ Clarity for the treatment of moderate to severe insomnia, designed to support Nexalin’s planned de novo submission to the U.S. Food and Drug Administration. The study is being conducted in collaboration with Lindus Health, a full-service clinical […]
What if sleep could help prevent Alzheimer’s disease? A new landmark study by researchers at Applied Cognition, a clinical-stage therapeutic company, points to the brain’s glymphatic system, its fluid-based “clean-up” pathway, as a key driver of overnight clearance of Alzheimer’s-linked proteins. The researchers found that during normal sleep, levels of amyloid beta and […]
Many Americans wind down their day with a scroll through the latest headlines, and that nightly habit may be taking a toll on their rest. According to a new survey from the American Academy of Sleep Medicine, over one-third (38%) of adults say using their phone or tablet before bed to view […]
Sunrise Group, a pioneer in medical device innovation and sleep care, today announced a new peer-reviewed study in Nature Communications Medicine. Sunrise developed the only home sleep test with respiratory effort measurement that has been validated against esophageal pressure, the reference standard. The study reveals that REMOV, the Sunrise-specific marker […]
A new Cedars Sinai Physician Associated Study is among the largest real-world evaluations of mandibular advancement device therapy for mild to moderate obstructive sleep apnea (OSA) and one of the first to examine a fully virtual, dentist-led care model from diagnosis through treatment and follow-up. Using the processes and care […]
Working the night shift, frequently flying across time zones or keeping an irregular sleep schedule does more than just leave us exhausted; it can fuel the risk of aggressive breast cancer. Exactly how and why this happens has remained a mystery, until now. A new study from the Texas A&M […]
