Throughout the day and night, cerebrospinal fluid (CSF) pulses through small fluid-filled channels surrounding blood vessels in the brain, called perivascular spaces, to flush out neuroinflammation and other neurological waste. A disruption to this vital process can lead to neurological dysfunction, cognitive decline, or developmental delays. For the first time, […]
Research/Studies
Study Identifies ‘Visual System’ Protein for Circadian Rhythm Stability
Teneurin-3 appears to help wire the brain in mice to resist changes in sleep and other cycles linked to changing light Scientists at the Johns Hopkins University School of Medicine and the National Institutes of Health have identified a protein in the visual system of mice that appears to be […]
Ingestible Electronic Device Detects Breathing Depression in Patients
Diagnosing sleep disorders such as sleep apnea usually requires a patient to spend the night in a sleep lab, hooked up to a variety of sensors and monitors. Researchers from MIT, Celero Systems, and West Virginia University hope to make that process less intrusive, using an ingestible capsule they developed […]
Signifier Medical Announces Publication of Randomized Trial Results of Neuromuscular Electrical Stimulation
Signifier Medical Technologies LLC (“Signifier” or the “Company”), a Boston-based medical technology company, is pleased to announce that the publication of AEGIS clinical trial results is in press at the ERJ Open Research. The objective of the trial was to determine whether patients with mild obstructive sleep apnea (OSA) would […]
Consistent Lack of Sleep is Related to Future Depressive Symptoms
Consistently sleeping less than five hours a night might raise the risk of developing depressive symptoms, according to a new genetic study led by UCL researchers. Historically, poor sleep has been seen as a side effect of mental ill health, but this study found that the link between sleep and […]
Newly Identified Structure in Circadian mRNA Period2 Affects Sleep-Wake Cycle
Circadian rhythms, the internal biological clocks that regulate our daily activities, are essential for maintaining health and well-being. While the role of transcription in these rhythms is well-established, a new study sheds light on the critical importance of post-transcriptional processes. The research, titled “Circadian ribosome profiling reveals a role for […]
Mount Sinai Researchers Create Automated OSA Severity Measure
Mount Sinai researchers have developed a novel, automated measure of analyzing sleep studies to determine the severity and risk of mortality in patients with obstructive sleep apnea. The study findings, which provide a validated tool to better manage sleep apnea and promote preventive care, were published in the American Journal […]
Astrocyte Brain Cells May Hold Key to Wakefulness
New animal research suggests that little-studied brain cells known as astrocytes are major players in controlling sleep need and may someday help humans go without sleep for longer without negative consequences such as mental fatigue and impaired physical health. Published in the Journal of Neuroscience, the study found that activating these […]
Could Cheap TENS Machines Replace CPAP?
A machine commonly used for pain relief has shown to improve breathing in patients with obstructive sleep apnea, a clinical trial has found. Results of the TESLA trial, published today in eClinical Medicine by researchers from King’s College London and Guy’s & St Thomas’ NHS Foundation Trust, shows the potential of a […]
How Mother and Infant Sleep Patterns Interact During First Two Years of Life
New mothers can expect sleep deprivation in the first few years of their baby’s life. But too little sleep can take a toll on the health of both mother and child. A new study from the University of Illinois Urbana-Champaign looks at maternal and infant sleep patterns, identifying predictors and providing recommendations for instilling […]













