Sleep and wakefulness are carefully balanced by a network of brain regions. Yet for many years, scientists couldn’t pinpoint exactly which neurons regulated sleep state transitions. New research tools and a deeper understanding of brain signaling have led to new discoveries in dopamine and norepinephrine signaling, offering novel insights into […]
Author: SleepWorld Magazine
Positive Topline Results from Second Phase 3 Trial of First OSA Pill
Apnimed, Inc. has announced positive topline results from its second pivotal Phase 3 clinical trial of Apnimed’s lead candidate AD109 (aroxybutynin 2.5mg/atomoxetine 75mg). LunAIRo was a 12-month study that evaluated the efficacy and safety of AD109 in adults with mild, moderate and severe OSA, across a wide range of weight […]
Phase 2 Study of Once-Daily Alixorexton in Patients With Narcolepsy Type 1
Alkermes plc today announced positive topline results from the randomized double-blind treatment period of the Vibrance-1 phase 2 study evaluating alixorexton in patients with narcolepsy type 1 (NT1). Alixorexton, formerly referred to as ALKS 2680, is the company’s novel, investigational, oral orexin 2 receptor (OX2R) agonist in phase 2 development as […]
Home Sleep Testing – No Business for Dentists?
Sleep apnea is a widespread sleep disorder affecting millions of Americans, yet many cases remain undiagnosed and untreated. Although the practice of screening patients with a home sleep test device by dentists is highly debated, as a board-certified sleep physician I firmly believe that dentists can play a crucial role […]
Sleep To Live Well Foundation Launches With Groundbreaking Sleep Wellness Report
The Sleep To Live Well Foundation issues an urgent warning in its groundbreaking 2025 State of Sleep Wellness Report, titled “THE SILENT EPIDEMIC: How Lack of Sleep Endangers Over Half of All Americans and Threatens Everyone.” The report unveils the Foundation’s initiatives to address this insufficient sleep crisis with Sleep Wellness—a holistic approach to […]
Sleep Bruxism and OSA
A Stronger Global Sleep Workforce
Over the years, the BRPT has played a pivotal role in shaping the field of sleep technology, setting high standards for professional competency and ensuring that patients receive quality sleep care that highlights the program’s evolution. One of the key ways in which the BRPT has done that is in […]
Nxera Pharma Receives $4.8M Milestone Payment from Centessa for ORX142 Trial
Nxera Pharma Co., Ltd. today announces that it will receive US$4.8 million in milestone payments from Centessa Pharmaceuticals pursuant to its research collaboration with Centessa. The milestones were achieved as Centessa initiated clinical development of ORX142, its second novel orexin receptor 2 (OX2R) agonist, following the recent clearance of an […]
Compumedics releases Falcon Home Sleep Testing Device in the United States
Compumedics Limited is excited to announce the launch of the Falcon, a Home Sleep Testing device now available for sale in the United States. The Falcon is designed to be simple to set up and deploy, enhancing both patient experience and workflow efficiency in home sleep testing. The Falcon HST […]
Are the Tariffs Keeping You Up at Night?
Sleep labs and suppliers across the U.S. are bracing for the economic ripple effects of sweeping new tariffs on imported goods. Consider, for example, a typical sleep diagnostic test. It might consist of a small machine, a box with plastic casing that houses electronics. Many of its components—the plastic or […]













