Sleep Disorders

Mosanna Therapeutics Reports Positive Results from the Phase 1 MOSAIC Study of MOS118 for Obstructive Sleep Apnea
Clinical Insights & Research Pharmacological Sleep Apnea Sleep Disorders

Mosanna Therapeutics Reports Positive Results from the Phase 1 MOSAIC Study of MOS118 for Obstructive Sleep Apnea

Mosanna Therapeutics, Inc., announced results from its Phase 1 MOSAIC study. MOS118 was safe and well tolerated across all doses, with no serious adverse events reported. These results support progression of the study into patients with OSA. “With these results we can now proceed to evaluate MOS118 in the patients it […]

Vanda Pharmaceuticals Announces Positive Phase III Results for HETLIOZ (tasimelteon) in Delayed Sleep-Wake Phase Disorder
Clinical Insights & Research Pharmacological Sleep Disorders

Vanda Pharmaceuticals Announces Positive Phase III Results for HETLIOZ (tasimelteon) in Delayed Sleep-Wake Phase Disorder

Vanda Pharmaceuticals Inc. announced positive topline results from its pivotal Phase III study of HETLIOZ® (tasimelteon) 20 mg in adults with Delayed Sleep-Wake Phase Disorder (DSWPD). Vanda intends to discuss these data with the U.S. Food and Drug Administration (FDA) and to submit a supplemental New Drug Application (sNDA) seeking […]

Lilly's Retatrutide Delivers Significant Weight Loss and A1C Reduction in Phase 3 Trial
Clinical Insights & Research Industry News Pharmacological Sleep Apnea

Lilly’s Retatrutide Delivers Significant Weight Loss and A1C Reduction in Phase 3 Trial

Lilly announced detailed results from TRIUMPH-2, a Phase 3 trial evaluating the efficacy and safety of retatrutide, an investigational, first-in-class GIP, GLP-1, and glucagon triple hormone receptor agonist, in adults with type 2 diabetes and obesity or overweight. At 80 weeks, all doses of retatrutide (4 mg, 9 mg, and […]

Women with Enlarged Breast Tissue More Likely to Experience Chronic Migraine, Neck Pain and Sleep Apnea, Study Finds
Clinical Insights & Research Patient Health Sleep Apnea Sleep Disorders Women's Health

Women with Enlarged Breast Tissue More Likely to Experience Chronic Migraine, Neck Pain and Sleep Apnea, Study Finds

Women with enlarged breast tissue, known medically as macromastia, may be more likely to experience chronic migraine, neck pain, certain spinal nerve disorders and obstructive sleep apnea, according to a new study by Wake Forest University School of Medicine researchers, published Tuesday in the journal Headache. The findings suggest enlarged […]

Parents in Distress: New Survey Highlights the Impact of Lost Sleep on Busy Parents
Industry News Patient Health Sleep Apnea Sleep Disorders

Parents in Distress: New Survey Highlights the Impact of Lost Sleep on Busy Parents

Aeroflow Sleep, a national durable medical equipment (DME) provider specializing in CPAP supplies, announced the results of a proprietary survey of 887 parents, which revealed a hidden health crisis happening due to parental sleep deprivation, with more than a quarter of respondents showcasing signs of undiagnosed sleep apnea.  Parents are […]

Oral Infigratinib Shows Benefits Beyond Growth in Children with Achondroplasia
Clinical Insights & Research Pediatric Health Pharmacological Sleep Apnea

Oral Infigratinib Shows Benefits Beyond Growth in Children with Achondroplasia

BridgeBio Pharma, Inc.,  presented new exploratory analyses from PROPEL 3, the global Phase 3 pivotal study of oral infigratinib in children living with achondroplasia, showing directionally favorable trends beyond growth across medical complications associated with achondroplasia, including sleep apnea, otitis media, and body composition. These data were presented at the […]

JOMS Study: Jaw Pain Condition May Signal Higher Risk for Sleep Apnea, Research Finds
Clinical Insights & Research Dental Sleep Medicine Patient Health Sleep Apnea

JOMS Study: Jaw Pain Condition May Signal Higher Risk for Sleep Apnea, Research Finds

Patients diagnosed with a temporomandibular disorder (TMD) are at increased risk for obstructive sleep apnea (OSA) compared to people without the disorder, according to a study published in the Journal of Oral and Maxillofacial Surgery (JOMS), the peer-reviewed official journal of the American Association of Oral and Maxillofacial Surgeons (AAOMS). TMD […]