Clinical Insights & Research

Lilly's Retatrutide Delivers Significant Weight Loss and A1C Reduction in Phase 3 Trial
Clinical Insights & Research Industry News Pharmacological Sleep Apnea

Lilly’s Retatrutide Delivers Significant Weight Loss and A1C Reduction in Phase 3 Trial

Lilly announced detailed results from TRIUMPH-2, a Phase 3 trial evaluating the efficacy and safety of retatrutide, an investigational, first-in-class GIP, GLP-1, and glucagon triple hormone receptor agonist, in adults with type 2 diabetes and obesity or overweight. At 80 weeks, all doses of retatrutide (4 mg, 9 mg, and […]

Women with Enlarged Breast Tissue More Likely to Experience Chronic Migraine, Neck Pain and Sleep Apnea, Study Finds
Clinical Insights & Research Patient Health Sleep Apnea Sleep Disorders Women's Health

Women with Enlarged Breast Tissue More Likely to Experience Chronic Migraine, Neck Pain and Sleep Apnea, Study Finds

Women with enlarged breast tissue, known medically as macromastia, may be more likely to experience chronic migraine, neck pain, certain spinal nerve disorders and obstructive sleep apnea, according to a new study by Wake Forest University School of Medicine researchers, published Tuesday in the journal Headache. The findings suggest enlarged […]

Oral Infigratinib Shows Benefits Beyond Growth in Children with Achondroplasia
Clinical Insights & Research Pediatric Health Pharmacological Sleep Apnea

Oral Infigratinib Shows Benefits Beyond Growth in Children with Achondroplasia

BridgeBio Pharma, Inc.,  presented new exploratory analyses from PROPEL 3, the global Phase 3 pivotal study of oral infigratinib in children living with achondroplasia, showing directionally favorable trends beyond growth across medical complications associated with achondroplasia, including sleep apnea, otitis media, and body composition. These data were presented at the […]

JOMS Study: Jaw Pain Condition May Signal Higher Risk for Sleep Apnea, Research Finds
Clinical Insights & Research Dental Sleep Medicine Patient Health Sleep Apnea

JOMS Study: Jaw Pain Condition May Signal Higher Risk for Sleep Apnea, Research Finds

Patients diagnosed with a temporomandibular disorder (TMD) are at increased risk for obstructive sleep apnea (OSA) compared to people without the disorder, according to a study published in the Journal of Oral and Maxillofacial Surgery (JOMS), the peer-reviewed official journal of the American Association of Oral and Maxillofacial Surgeons (AAOMS). TMD […]

AI Identifies Previously Unrecognized Health Insights in Routine Sleep Studies
Artificial Intelligence Clinical Insights & Research Technology

AI Identifies Previously Unrecognized Health Insights in Routine Sleep Studies

A novel AI model can use information collected during routine sleep studies to identify patients’ long-term health risks, according to a new study published in Nature Communications. Developed by a multidisciplinary research team, the model uncovered hidden sleep patterns linked to risks including heart disease, cognitive decline and death. The […]

New Study Uses Sleep Monitoring and AI to Detect Alzheimer's
Artificial Intelligence Clinical Insights & Research Technology

New Study Uses Sleep Monitoring and AI to Detect Alzheimer’s

Researchers from Universidad Carlos III de Madrid (UC3M) and Hospital Universitario Severo Ochoa in Leganés, part of the public health network of the Comunidad de Madrid, have developed a methodology that uses artificial intelligence (AI) to analyze brain electrical activity during sleep and facilitate the early diagnosis of Alzheimer’s. The […]